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Aldactone prescription: Spironolactone is used as a diuretic to remove the excess fluid caused by congestive heart failure, cirrhosis of the liver, and kidney disease. It can also be used to treat elevated blood pressure in combination with other drugs and in resistant cases of low potassium (hypokalemia). Spironolactone is also used to counteract the effects of excessive adrenal aldosterone production. Aldosterone overproduction can occur from a tumor in the adrenal gland, or when enlarged adrenal glands produce an excessive amount of aldosterone. One of the main functions of the kidneys is to retain salt (sodium chloride) and water. In patients with heart failure and cirrhosis, increased levels of a hormone produced by the adrenal glands, called aldosterone, causes salt and fluid retention by the kidneys. Spironolactone inhibits the action of aldosterone causing the kidneys to excrete salt and fluid while retaining potassium. Therefore, spironolactone is classified as a potassium-sparing medication that promotes the output of urine (diuretic).
Aldactone use: Spironolactone is in a class of drugs called potassium-sparing diuretics (water pill). It is used to reduce the amount of fluid in your body without causing the loss of potassium. Spironolactone is used to treat edema (swelling) and hypertension (high blood pressure).
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Why is this drug prescribed?
Spironolactone belongs to a group of drugs known as the potassium-sparing diuretics. It acts in the kidney to remove excess water from the blood into the urine. Spironolactone blocks the actions of a hormone called aldosterone, which causes an increase in the removal of salts such as sodium from the blood. This removal of salts causes water to be drawn out of the blood and into the kidneys, where it is then excreted in the urine. Removing water from the blood causes a decrease in the volume of fluid circulating through the blood vessels. This drop in fluid volume decreases the effort required by the heart to pump blood around the body.
There are many conditions which may lead to an accumulation of fluid in the body. Spironolactone is commonly used in conditions such as heart failure, where the pumping mechanism of the heart is less effective. It is used to relieve the symptoms of heart failure, such as the shortness of breath seen with fluid on the lungs. It is also used to remove excess fluid associated with liver failure, as well as in the treatment of excessive levels of aldosterone.
Spironolactone does not increase the loss of potassium from the body in the urine, therefore there is less risk of developing low potassium levels in the blood. When it is used alone it has a weak effect, therefore it is often used in combination with other diuretics.
Treatments
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